Organophosphate has three major applications; insecticides, petroleum additives, and modifiers of plastic. According to the latent period, orgaophosphate intoxication is classified by acute syndrome, intermediate syndrome, organophasphate induced
delayed polyneuropathy(OPIDP). Acute syndrome, occuring shortly after exposure, due to an excessive acetylcholine effect on muscarinic receptors, is characterized by gastrointestinal distress, miosis, lacrimation, and no weakness. As a treatment,
atropinization is effective. Intermediate syndrome, occuring 12 to 96 hours after exposure, due to an acetylchoine effect on nicotinic receptors, results in limb and respiratory muscle weakness. There is no effective treatment. OPIDP is less
common
than
the cholinergic reaction and occurs after a latent period of 7 to 2l days. The initial neurological symptom of OPIDP include cramping calf pain, tingling, burning sensations in the feet and occasionally in the hands. Weakness is an early and
invariable
finding. Spasticity and ataxia can be seen in the case of involving the central nervous system. There is also no specific treatment. The prognosis in mind affected individuals, presumably with less exposure, has been good. They generally make a
nearly
complete recovery. Others with more severe initial deficit are left with varing degrees of morbidity, which include sequalae of both peripheral, central nervous system damage, and recovery is slow and usually incomplete.
We experienced a case of organophosphate intoxication which included acute syndrome, intermediate syndrome and OPIDP. At the time of transfer to rehabilitation department, he was a quadriplegia, who had the delayed symptome of organophosphate
intoxication
We report an example of the quadriplegia which results from organophosphate intoxication.
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